I couldn’t open a *.MOV file I just exported from Adobe Premiere, on Quicktime.
I tried changing the extension to *.WMV and opened on VLC player, and it worked fine.
After hours of looking for answers to error 2048, I found this magic tip (It worked for me):
Delete the temporarily Quicktime files in the folder
C:\Documents and Settings\[user]\Local Settings\Application Data\Apple Computer\QuickTime\downloads\